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KMID : 0617320000090010066
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Journal of Pharmacetical Sceiences Ewha Womans University
2000 Volume.9 No. 1 p.66 ~ p.68
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5-(4-Hydroxyphenethenyl)-4,7-dime-thoxycoumarin, a New Constituent of Monotes engleri
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Seo Eun-Kyoung
Chai Hee-Byung
Chagwedera, Tangai E.
Farnsworth, Norman R.
Cordell, Geoffrey A.
Pezzuto, John M.
Kinghorn, A. Douglas
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Abstract
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A new coumarin, 5-(4-hydroxyphenethenyl)-4,7-dimethoxycoumarin (1) was isolated from the combined ethyl acetate extracts of the root bark, root wood and stem bark of Monotes engleri, and found to be cytotoxic against two cell lines in a human tumor panel. Its structure was determined on the basis of spectroscopic methods.
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